Aggresive Ectopic ACTH production causing Cushing's
نویسندگان
چکیده
منابع مشابه
Ectopic ACTH Production: Diagnosis, Treatment and Prognosis
A 69-year-old woman presented with a four-week history of facial and bilateral leg swelling. She also described symptoms of proximal myopathy. Her past medical history included osteoporosis and osteoarthritis. Routine medication was a weekly bisphosphonate, aspirin and St John’s Wort. Clinical examination identified bilateral pitting oedema to the knees and Cushingoid facies. Her blood pressure...
متن کاملAn extra-adrenal abdominal pheochromocytoma causing ectopic ACTH syndrome.
We report a 55-year-old woman with ectopic adrenocorticotropin (ACTH) secretion caused by extra-adrenal pheochromocytoma. The patient presented with a 6-month history of hypertension and diabetes mellitus. Her serum and urinary cortisol levels were extremely high and dexamethasone failed to suppress the cortisol secretion. Her plasma ACTH levels were also elevated (>300 pg/mL) and irresponsive ...
متن کامل[Ectopic ACTH syndrome].
Cushing症 候群 は慢性的なコルチゾール過剰症であ り,放 置すると脳血管障害,糖 尿病,感 染症などで死 亡する.し たがって,適 切な診断 と治療が重要である. 表1に 示すように,ACTH依 存性Cushing症 候群 に は脳下垂体のACTH産 生腫によるGushing病 と異所 性ACTH症 候群があ り,ACTH非 依存性Cushing 症候群 には副腎原発性病変,医 原性 によるCushing症 候群がある.中 で もGushing病 と異所性ACTH症 候 群の鑑別 は治療法の選択 と関連 して重要である.我 々 が経験 した異所性ACTH症 候群を紹介する. 【症例】64歳,女 性.1993年 頃か ら顔面,下 腿の浮 腫,し びれ感 と全身の疼痛(肩 甲部,胸 部,腰 背部) を自覚するようになったため某院に入院した.糖 尿病, 高血圧,骨 粗鬆症 と診断さ...
متن کاملEctopic ACTH production in carcinoma of the lung.
Immunoreactive ACTH was found in almost all tissue extracts of lung carcinoma from patients without clinical evidence of Cushing's syndrome; i.e. 14 of 15 primary tumors, nine of nine metastatic lymph nodes, and four of four metastatic liver nodules contained immunoreactive ACTH. The incidence of ACTH in extracts of other tumor types was much lower. Comparable normal tissues contained no detect...
متن کاملResponse of ectopic prostatic ACTH production to metyrapone.
Case report A 63-year-old man who 3 years previously had undergone a transurethral prostatic resection for adenocarcinoma presented with a 2-month history of 'euphoric' behaviour followed by an excessive thirst and ankle swelling. He was a non-smoker and had been taking ethinyl oestradiol (stilboestrol) 3 mg daily since the prostatic resection. Initial examination revealed an extravagant and ex...
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ژورنال
عنوان ژورنال: Endocrine Abstracts
سال: 2017
ISSN: 1479-6848
DOI: 10.1530/endoabs.50.ep084